The wet granulated material obtained during the granulation process (High shear Mixer Granulator MIC) is dried in fluid bed through the combination of moisture by forced-air convection. In this unit operation, the granulated material must be fluidized by hot and dehumidified air in order to produce an efficient of the process an quality product:
With higher temperature, Iower humidity and higher air flow rate, Iower drying time Will be required. However, each parameter must be carefully defined for each type of granulated product.
CONCEPTION
The fluid bed dryer ESSICCA uses devices and sensors driven by specific drying programs which allow the optimization of the process critical parameters.
The inlet air temperature signa/ which is measured by the air sensor in contact with the fluidized product, which should not exceed the critica/ temperature of the product (pharmaceutica/ stability)
Inlet air humidity is kept at a narrow dew point range in order to get reproducibility batch to batch.
The air flow rate is configured based on the Minimum
Fluidization Velocity, MFV (see experimental protocol)
In optimized conditions, the drying process is short and reproducible allowing high quality products.
