GMP regulations generally require terminal sterilization of parenteral products after packaging. Getinge GEC (circulating-water terminal sterilizers or water-cascade sterilizers) are primarily intended for large volumes of liquids in sealed glass or plastic containers. They assure sterility of the product in a rapid cycle, yet gentle enough to protect the integrity and shape of components, products and packaging. A wide range of sterilization cycles gives excellent application versatility. By using water recirculated by a high-capacity pump, Getinge GEC terminal sterilizers provide efficient utilization with high product throughput.